Mitosis: Spindle Assembly, Chromosome Dynamics, and Cytokinesis
Students will be introduced to the overall process of photosynthesis, understanding how plants convert light energy into chemical energy.
Key Questions
- Explain the molecular events underpinning each phase of mitosis from nuclear envelope breakdown through cytokinesis, focusing on kinetochore-microtubule attachment and the spindle assembly checkpoint mechanism that ensures equal chromosome segregation.
- Analyse how errors in spindle assembly or checkpoint signalling can generate aneuploidy, and evaluate the link between aneuploidy, chromosomal instability, and malignant transformation.
- Compare cytokinesis in plant and animal cells at the molecular and structural level, explaining why the presence of a rigid cell wall in plant cells necessitates the formation of a cell plate rather than a contractile ring.
MOE Syllabus Outcomes
Suggested Methodologies
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