Singapore · MOE Syllabus Outcomes
JC 1 Biology
This course explores the fundamental principles governing life from the molecular level to complex ecosystems. Students analyze the intricate relationship between structure and function while investigating how genetic information drives biological diversity and continuity.

Molecular Foundations and Cellular Architecture
An investigation into the biochemical building blocks of life and the specialized organelle structures that maintain cellular homeostasis.
Examining how the unique properties of water, carbohydrates, lipids, and proteins support life processes.
Analyzing the fluid mosaic model and the mechanisms cells use to regulate the movement of substances.
Exploring how compartmentalization allows for specialized biochemical pathways within eukaryotic cells.

Genetic Blueprints and Information Flow
A study of DNA structure, replication, and the mechanisms by which genes are expressed as functional proteins.
Understanding the molecular basis of inheritance and the high fidelity of DNA synthesis.
Tracing the flow of information from the nucleus to the ribosome to build polypeptides.
Investigating how changes in the nucleotide sequence lead to genetic variation and disease.

Energy Transformations in Living Systems
Analyzing the metabolic pathways of respiration and photosynthesis that power biological work.
Studying the kinetics of enzymes and the factors that regulate their activity in metabolic pathways.
Examining the breakdown of glucose to generate ATP through aerobic and anaerobic pathways.
Investigating the conversion of light energy into chemical energy within the chloroplast.

The Cell Cycle and Inheritance
Exploring how genetic material is replicated and distributed during cell division and the patterns of inheritance.
Analyzing the regulation of the cell cycle and the consequences of uncontrolled cell division.
Investigating how meiosis generates genetic diversity through recombination and independent assortment.
Applying the laws of inheritance to predict phenotypic ratios in offspring.

Evolution and the Diversity of Life
Examining the mechanisms of evolution and the evidence for the common ancestry of all life forms.
Studying how selective pressures drive changes in allele frequencies within populations.
Investigating the processes that lead to the formation of new species and the reconstruction of evolutionary history.
Evaluating the physical evidence for macroevolutionary changes over geological time.

Biological Systems and the Environment
Analyzing the flow of energy and cycling of nutrients within ecosystems and the impact of human activity.
Understanding the interactions between biotic and abiotic components in maintaining ecosystem stability.
Evaluating the biological consequences of global warming and habitat fragmentation.
Investigating how human activities disrupt the nitrogen and carbon cycles.