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Browse by Grade: 11th Grade

United States · Common Core State Standards

11th Grade Biology

An advanced exploration of life from the molecular level to the global biosphere. Students investigate the mechanisms of inheritance, the evidence for evolution, and the intricate connections within ecosystems to understand the challenges facing modern biology.

6 units·74 topics·Ages 16-17

01The Molecular Basis of Life

13 topics·Weeks 1-9

Explores the fundamental biochemistry of cells and the specialized structures that allow life to maintain homeostasis. Students analyze how carbon-based molecules and organelles work together to sustain living systems.

Introduction to Biological Chemistry

Introduces the basic chemical principles essential for understanding biological systems, including atomic structure, bonding, and properties of water.

Concept MappingThink-Pair-Share
Carbohydrates and Lipids

Investigates the structure and function of carbohydrates as energy sources and structural components, and lipids for energy storage, membrane formation, and signaling.

JigsawCase Study Analysis
Proteins: Structure and Function

Explores the diverse roles of proteins as enzymes, structural components, transporters, and signaling molecules, emphasizing their complex 3D structures.

Inquiry CircleConcept Mapping
Nucleic Acids and ATP

Focuses on the structure and function of DNA and RNA in genetic information storage and transfer, and ATP as the primary energy currency of the cell.

Stations RotationThink-Pair-Share
Cell Structure and Organelles

Examines the fundamental differences between prokaryotic and eukaryotic cells and the specialized functions of eukaryotic organelles.

Gallery WalkConcept Mapping
Plasma Membrane and Selective Permeability

Focuses on the fluid mosaic model of the plasma membrane and its role in regulating the passage of substances into and out of the cell.

Simulation GameInquiry Circle
Passive and Active Transport

Explores the mechanisms of passive transport (diffusion, osmosis, facilitated diffusion) and active transport (pumps, endocytosis, exocytosis) across cell membranes.

Stations RotationCase Study Analysis
Enzymes and Metabolic Pathways

Examines the role of enzymes as biological catalysts, factors affecting enzyme activity, and their integration into metabolic pathways.

Inquiry CircleProblem-Based Learning
Photosynthesis: Light Reactions

Focuses on the capture of light energy by pigments, the electron transport chain, and the production of ATP and NADPH in the thylakoid membranes.

Simulation GameConcept Mapping
Photosynthesis: Calvin Cycle

Examines the carbon fixation, reduction, and regeneration phases of the Calvin cycle, leading to the synthesis of glucose.

JigsawStations Rotation
Cellular Respiration: Glycolysis and Krebs Cycle

Covers the breakdown of glucose into pyruvate, the subsequent conversion to acetyl-CoA, and the reactions of the Krebs cycle, generating ATP, NADH, and FADH2.

Inquiry CircleConcept Mapping
Cellular Respiration: Oxidative Phosphorylation

Focuses on the electron transport chain and chemiosmosis, where the majority of ATP is produced through the flow of electrons and proton gradients.

Simulation GameCase Study Analysis
Fermentation and Anaerobic Pathways

Examines alternative energy-generating pathways in the absence of oxygen, including lactic acid and alcoholic fermentation.

Problem-Based LearningThink-Pair-Share

02Information Storage and Transfer

13 topics·Weeks 1-9

Focuses on the role of DNA as the blueprint of life and the processes of protein synthesis and cell division. Students examine how genetic information is regulated and passed between generations.

History and Structure of DNA

Explores the historical discoveries leading to the understanding of DNA's double helix structure and its components.

Stations RotationTimeline Challenge
DNA Replication Mechanisms

Covers the semi-conservative model of DNA replication, including the roles of various enzymes and the leading/lagging strand synthesis.

Simulation GameJigsaw
From Gene to Protein: Transcription

Traces the process of transcription, where DNA is used as a template to synthesize messenger RNA (mRNA).

Peer TeachingConcept Mapping
From Gene to Protein: Translation

Explores the process of translation, where mRNA codons are read by ribosomes to synthesize a polypeptide chain with the help of tRNA.

Simulation GameStations Rotation
Gene Regulation and Expression

Examines how gene expression is controlled in prokaryotic and eukaryotic cells, allowing for cell differentiation and response to environmental cues.

Case Study AnalysisInquiry Circle
Mutations and Their Effects

Investigates different types of mutations (point, frameshift, chromosomal) and their potential consequences on protein function and organismal phenotype.

Problem-Based LearningDocument Mystery
The Cell Cycle: Interphase

Focuses on the stages of interphase (G1, S, G2) where cells grow, replicate their DNA, and prepare for division.

Concept MappingThink-Pair-Share
Mitosis: Nuclear Division

Examines the stages of mitosis (prophase, metaphase, anaphase, telophase) and the precise separation of sister chromatids.

Stations RotationSimulation Game
Cell Cycle Regulation and Checkpoints

Analyzes the internal and external controls that regulate the cell cycle, including checkpoints and growth factors.

Case Study AnalysisInquiry Circle
Cancer: Uncontrolled Cell Growth

Investigates the molecular basis of cancer, including mutations in proto-oncogenes and tumor suppressor genes, and the characteristics of cancer cells.

Fishbowl DiscussionCase Study Analysis
Stem Cells and Differentiation

Explores the properties of stem cells, their potential for differentiation, and their applications in regenerative medicine.

Socratic SeminarExpert Panel
Viruses and Their Life Cycles

Examines the structure, replication strategies, and impact of viruses on host cells and organisms.

Case Study AnalysisConcept Mapping
Prions and Viroids

Introduces non-viral infectious agents like prions (misfolded proteins) and viroids (naked RNA) and their unique mechanisms of disease.

Document MysteryThink-Pair-Share

03Inheritance and Variation

13 topics·Weeks 10-18

Investigates the patterns of inheritance from Mendelian genetics to complex modern genomics. Students apply probability and pedigree analysis to predict genetic outcomes.

Introduction to Meiosis

Introduces the purpose of meiosis in sexual reproduction and the reduction of chromosome number.

Concept MappingThink-Pair-Share
Meiosis I: Separating Homologous Chromosomes

Examines the stages of Meiosis I, including prophase I (crossing over), metaphase I, anaphase I, and telophase I.

Stations RotationSimulation Game
Meiosis II and Genetic Variation

Focuses on the stages of Meiosis II, where sister chromatids separate, resulting in four haploid gametes, and summarizes sources of genetic variation.

Gallery WalkJigsaw
Mendel's Laws of Inheritance

Explores Mendel's experiments with pea plants, leading to the laws of segregation and independent assortment.

Problem-Based LearningThink-Pair-Share
Beyond Mendelian Genetics: Incomplete Dominance and Codominance

Investigates inheritance patterns where alleles are not strictly dominant or recessive, such as incomplete dominance and codominance.

Case Study AnalysisStations Rotation
Multiple Alleles and Polygenic Inheritance

Explores traits determined by more than two alleles (e.g., ABO blood groups) and traits influenced by multiple genes (polygenic inheritance).

Problem-Based LearningGallery Walk
Sex-Linked Inheritance and Pedigrees

Focuses on genes located on sex chromosomes and the use of pedigree charts to track inheritance patterns of genetic disorders.

Case Study AnalysisDocument Mystery
Chromosomal Abnormalities

Investigates numerical and structural chromosomal abnormalities, their causes (e.g., nondisjunction), and associated genetic disorders.

Inquiry CircleCase Study Analysis
Genetic Engineering: Recombinant DNA

Introduces the tools and techniques of genetic engineering, including restriction enzymes, plasmids, and the creation of recombinant DNA.

Simulation GameProject-Based Learning
CRISPR and Gene Editing

Explores the revolutionary CRISPR-Cas9 system for precise gene editing and its implications for treating genetic diseases.

Socratic SeminarFormal Debate
Cloning and Reproductive Technologies

Discusses different types of cloning (reproductive and therapeutic) and other assisted reproductive technologies, along with their ethical dimensions.

Philosophical ChairsCase Study Analysis
Forensic Genetics and DNA Fingerprinting

Examines the use of DNA profiling techniques in forensic science, paternity testing, and identification.

Document MysteryCase Study Analysis
Genomics and Personalized Medicine

Introduces the field of genomics, the Human Genome Project, and the promise of personalized medicine based on an individual's genetic profile.

Expert PanelWorld Café

04Evolution and the History of Life

11 topics·Weeks 10-18

Reviews the evidence for evolution by natural selection and the mechanisms that lead to speciation. Students analyze fossil records, comparative anatomy, and molecular data.

Early Earth and Origin of Life

Explores hypotheses about the conditions on early Earth and the scientific theories regarding the abiotic synthesis of organic molecules and the first cells.

Inquiry CircleConcept Mapping
Fossil Record and Geologic Time

Examines how fossils provide evidence for evolution, methods of dating fossils, and the major events in Earth's geologic history.

Stations RotationTimeline Challenge
Comparative Anatomy and Embryology

Evaluates homologous, analogous, and vestigial structures, and similarities in embryonic development as evidence for common ancestry.

Gallery WalkThink-Pair-Share
Molecular Evidence for Evolution

Focuses on DNA, RNA, and protein sequence comparisons, and molecular clocks as powerful tools to infer evolutionary relationships.

Case Study AnalysisInquiry Circle
Darwin, Wallace, and Natural Selection

Introduces the theory of evolution by natural selection, including observations that led to its formulation and its core principles.

Socratic SeminarDocument Mystery
Mechanisms of Evolution: Genetic Drift and Gene Flow

Explores other mechanisms of evolution, including genetic drift (bottleneck and founder effects) and gene flow, and their impact on allele frequencies.

Simulation GameProblem-Based Learning
Adaptation and Fitness

Focuses on how organisms develop adaptations to their environment, the concept of fitness, and different types of natural selection (directional, disruptive, stabilizing).

Case Study AnalysisDecision Matrix
Hardy-Weinberg Equilibrium and Population Genetics

Introduces the Hardy-Weinberg principle as a null hypothesis for evolution and its use in calculating allele and genotype frequencies in populations.

Problem-Based LearningInquiry Circle
Reproductive Isolation and Speciation

Examines prezygotic and postzygotic reproductive barriers and the processes (allopatric and sympatric) that lead to the formation of new species.

JigsawConcept Mapping
Patterns of Evolution: Adaptive Radiation and Coevolution

Explores large-scale evolutionary patterns, including adaptive radiation, convergent evolution, and coevolutionary relationships.

Case Study AnalysisGallery Walk
Phylogenetic Trees and Cladograms

Focuses on interpreting and constructing phylogenetic trees and cladograms to represent evolutionary relationships among organisms.

Stations RotationProject-Based Learning

05Ecology and Environmental Dynamics

13 topics·Weeks 19-27

Examines the interactions between organisms and their environment. Students study population dynamics, energy flow, and the impact of human activity on biodiversity.

Levels of Ecological Organization

Introduces the hierarchy of ecological study, from individual organisms to the biosphere, and key ecological terms.

Concept MappingThink-Pair-Share
Population Growth Models

Analyzes exponential and logistic growth models, carrying capacity, and factors that regulate population size.

Simulation GameProblem-Based Learning
Human Population Dynamics

Investigates the historical and current trends in human population growth, demographic transitions, and their environmental impacts.

Decision MatrixTown Hall Meeting
Community Interactions: Competition and Predation

Explores interspecific and intraspecific competition, predator-prey relationships, and their ecological consequences.

Role PlayCase Study Analysis
Community Interactions: Symbiosis

Examines different types of symbiotic relationships: mutualism, commensalism, and parasitism, and their ecological significance.

JigsawGallery Walk
Food Chains, Food Webs, and Trophic Levels

Focuses on the flow of energy through ecosystems, constructing food chains and webs, and the concept of trophic levels.

Concept MappingProject-Based Learning
Energy Pyramids and Ecological Efficiency

Examines the transfer of energy between trophic levels, the 10% rule, and the implications for biomass and numbers pyramids.

Problem-Based LearningSimulation Game
Biogeochemical Cycles: Water and Carbon

Investigates the movement of water and carbon through the Earth's atmosphere, oceans, land, and living organisms.

JigsawConcept Mapping
Biogeochemical Cycles: Nitrogen and Phosphorus

Examines the cycling of nitrogen and phosphorus, their importance for life, and the impact of human activities on these cycles.

Stations RotationInquiry Circle
Biodiversity and Ecosystem Services

Defines biodiversity at different levels (genetic, species, ecosystem) and explores the essential services ecosystems provide to humans.

World CaféGallery Walk
Threats to Biodiversity

Investigates major threats to biodiversity, including habitat loss, invasive species, pollution, climate change, and overexploitation.

Case Study AnalysisDecision Matrix
Climate Change and Its Ecological Impacts

Examines the causes and consequences of climate change, including its effects on ecosystems, species distribution, and phenology.

Town Hall MeetingSocratic Seminar
Conservation Strategies and Sustainability

Focuses on approaches to conserve biodiversity, including protected areas, restoration ecology, and sustainable practices.

Project-Based LearningCollaborative Problem-Solving

06Human Systems and Integration

11 topics·Weeks 28-36

A study of the major organ systems of the human body and how they collaborate to maintain health. Students investigate the relationship between system structure and physiological function.

Introduction to Human Body Systems

Overview of the major organ systems, their primary functions, and the concept of homeostasis in the human body.

Concept MappingJigsaw
The Nervous System: Structure and Function

Examines the organization of the nervous system (CNS, PNS), neuron structure, and the transmission of nerve impulses.

Simulation GameStations Rotation
The Brain and Senses

Focuses on the major regions of the brain and their functions, as well as the mechanisms of sensory perception.

Case Study AnalysisInquiry Circle
The Endocrine System and Hormones

Compares the endocrine system's role in long-term regulation through hormones, glands, and feedback mechanisms.

Concept MappingCase Study Analysis
The Cardiovascular System

Examines the structure and function of the heart, blood vessels, and blood, and the regulation of blood pressure.

Simulation GameExperiential Learning
The Respiratory System

Focuses on the anatomy of the respiratory tract, the mechanics of breathing, and gas exchange in the lungs.

Stations RotationInquiry Circle
The Digestive System and Nutrition

Traces the path of food through the digestive tract, the roles of enzymes, and the absorption of nutrients.

JigsawConcept Mapping
The Excretory System

Examines the structure and function of the kidneys, the process of urine formation, and the regulation of water and salt balance.

Simulation GameCase Study Analysis
Nonspecific Defenses and Innate Immunity

Introduces the body's first and second lines of defense, including physical barriers, phagocytes, and inflammation.

Concept MappingThink-Pair-Share
Specific Defenses and Adaptive Immunity

Focuses on the adaptive immune system, including B cells, T cells, antibodies, and immunological memory.

Role PlayJigsaw
Vaccines and Immune Disorders

Examines the principles of vaccination, the development of immunity, and common immune system disorders (allergies, autoimmune diseases, immunodeficiency).

Case Study AnalysisExpert Panel