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Browse by Grade: 10th Grade

United States · Common Core State Standards

10th Grade Biology

This course explores the fundamental principles of life from microscopic molecular interactions to global ecosystem dynamics. Students investigate how organisms maintain homeostasis, transfer genetic information, and evolve over time through evidence based inquiry.

4 units·50 topics·Ages 15-16

01The Chemistry of Life and Cell Structure

13 topics·Weeks 1-9

Students examine the chemical foundations of biology, focusing on how specialized structures within cells help organisms maintain stability and process energy.

Water's Unique Properties for Life

Exploring the unique properties of water that allow life to exist on Earth, from polarity to high specific heat.

Stations RotationThink-Pair-ShareConcept Mapping
Carbohydrates and Lipids: Structure & Function

An analysis of carbohydrates and lipids, focusing on their specific roles in energy storage, structure, and signaling.

Gallery WalkJigsawTrading Cards
Proteins and Nucleic Acids: Information & Action

Investigating the diverse roles of proteins and nucleic acids as the workhorses and information carriers of the cell.

JigsawConcept MappingPeer Teaching
Enzymes: Biological Catalysts

Investigating how biological catalysts lower activation energy to facilitate life-sustaining chemical reactions.

Simulation GameCase Study AnalysisInquiry Circle
Prokaryotic vs. Eukaryotic Cells

Comparing the structural complexity of bacteria to the compartmentalized organelles of plant and animal cells.

Mock TrialSocratic SeminarPeer Teaching
Organelles: Structure and Function

A deep dive into the specialized roles of key organelles like mitochondria, chloroplasts, and the nucleus.

Stations RotationGallery WalkConcept Mapping
The Endomembrane System in Action

Tracing the path of protein production from the nucleus through the ER and Golgi apparatus to the cell surface.

Flipped ClassroomRole PlayEscape Room
Cell Membrane: Fluid Mosaic Model

Analyzing the fluid mosaic model and the components that make up the cell's outer boundary.

Concept MappingThink-Pair-ShareSimulation Game
Passive Transport: Diffusion & Osmosis

Investigating the physics of passive transport mechanisms, including simple diffusion, facilitated diffusion, and osmosis.

Simulation GameInquiry CircleGraffiti Wall
Active Transport and Bulk Transport

Analyzing how cells use energy to move substances against their concentration gradients and transport large molecules.

Simulation GameCase Study AnalysisProblem-Based Learning
Cellular Communication and Signaling

Understanding how cells receive and respond to chemical signals from their environment or other cells.

Socratic SeminarCase Study AnalysisChalk Talk
Cell Junctions and Adhesion

Exploring the different types of cell junctions and their roles in tissue formation and communication.

Concept MappingGallery WalkJigsaw
The Extracellular Matrix

Investigating the complex network of molecules outside animal cells and its role in support and signaling.

Think-Pair-ShareCase Study AnalysisConcept Mapping

02Energy Flow: Photosynthesis and Respiration

13 topics·Weeks 10-18

A study of how matter and energy flow through organisms via the complementary processes of capturing light and breaking down carbon compounds.

ATP: The Energy Currency of the Cell

Examining the structure of adenosine triphosphate and how it powers cellular work through phosphorylation.

Concept MappingThink-Pair-ShareMock Trial
Photosynthesis Overview and Pigments

An introduction to photosynthesis, including the role of chloroplasts and light-absorbing pigments.

Flipped ClassroomGallery WalkConcept Mapping
The Light-Dependent Reactions

Investigating how chlorophyll captures solar energy to produce high-energy electrons and oxygen.

Simulation GameSocratic SeminarJigsaw
The Calvin Cycle and Carbon Fixation

Analyzing how plants use CO2 and energy from light reactions to build stable organic sugars.

Flipped ClassroomGallery WalkProblem-Based Learning
Cellular Respiration: An Overview

An introduction to cellular respiration, including its stages and overall purpose.

Concept MappingThink-Pair-ShareRound Robin
Glycolysis: The First Step

Studying the universal first step of energy extraction from glucose in the cytoplasm.

Stations RotationSimulation GamePeer Teaching
Anaerobic Pathways: Fermentation

Investigating the variations of fermentation that occur in the absence of oxygen.

Problem-Based LearningStations RotationCase Study Analysis
Pyruvate Oxidation and the Krebs Cycle

Tracing the breakdown of pyruvate in the mitochondria to release carbon dioxide and capture electrons.

Mock TrialWalk and TalkConcept Mapping
The Electron Transport Chain and Chemiosmosis

Analyzing how a proton gradient drives the synthesis of large amounts of ATP via ATP synthase.

Simulation GameSocratic SeminarExpert Panel
Metabolic Interconnections

Exploring how different macromolecules (fats, proteins) can enter the cellular respiration pathways.

Concept MappingJigsawCase Study Analysis
Factors Affecting Photosynthesis & Respiration

Investigating environmental factors that influence the rates of these key metabolic processes.

Inquiry CircleSimulation GameProblem-Based Learning
The Global Carbon Cycle

Connecting cellular metabolism to the movement of carbon through the atmosphere, oceans, and biosphere.

Project-Based LearningFormal DebateDocument Mystery
Energy Flow in Ecosystems

Exploring how energy is transferred through trophic levels and the concept of ecological pyramids.

JigsawConcept MappingSimulation Game

03The Cell Cycle and Molecular Genetics

13 topics·Weeks 19-27

This unit focuses on the mechanisms of inheritance, the structure of DNA, and how genetic variation is produced.

DNA Structure and Discovery

Tracing the history of the double helix discovery from Griffith to Watson, Crick, and Franklin.

Document MysteryTimeline ChallengeMock Trial
DNA Replication Mechanisms

A detailed look at the semi-conservative replication process and the enzymes involved.

Simulation GameStations RotationPeer Teaching
Chromosomes and Karyotypes

Exploring the organization of DNA into chromosomes and how karyotypes are used to analyze genetic material.

Gallery WalkCase Study AnalysisConcept Mapping
The Cell Cycle: Interphase

Investigating the stages of interphase (G1, S, G2) where cells grow and prepare for division.

Flipped ClassroomThink-Pair-ShareStations Rotation
Mitosis and Cytokinesis

Exploring the phases of nuclear division that produce genetically identical daughter cells.

Mock TrialStations RotationJigsaw
Cell Cycle Regulation and Cancer

Investigating the checkpoints that control cell growth and the consequences of their failure.

Case Study AnalysisSocratic SeminarExpert Panel
Transcription: From DNA to RNA

The process of synthesizing messenger RNA as a mobile copy of genetic instructions.

Mock TrialFlipped ClassroomThink-Pair-Share
Translation: Building Proteins

How ribosomes and tRNA translate the triplet codons of mRNA into a polypeptide chain.

Role PlayDecision MatrixStations Rotation
Gene Expression and Epigenetics

Exploring how cells turn genes on and off in response to internal and external signals.

Case Study AnalysisPhilosophical ChairsConcept Mapping
Mutation Types and Effects

Analyzing point mutations, frameshifts, and chromosomal aberrations and their phenotypic outcomes.

Problem-Based LearningGallery WalkSimulation Game
Viruses: Structure and Replication

Investigating the basic structure of viruses and their mechanisms for infecting host cells and replicating.

Case Study AnalysisSimulation GameJigsaw
Bacterial Genetics and Plasmids

Exploring genetic exchange in bacteria and the role of plasmids in antibiotic resistance.

Document MysteryProblem-Based LearningSocratic Seminar
Biotechnology: Recombinant DNA

An introduction to the techniques used to combine DNA from different sources, forming recombinant DNA.

Flipped ClassroomStations RotationConcept Mapping

04Inheritance and Biotechnology

11 topics·Weeks 28-36

Investigating the patterns of heredity and the modern tools used to manipulate genetic information.

Meiosis and Gametogenesis

The specialized cell division that reduces chromosome number and creates genetic diversity.

Mock TrialJigsawConcept Mapping
Mendelian Genetics and Probability

Applying Mendel's laws of segregation and independent assortment to predict trait inheritance.

Problem-Based LearningStations RotationGallery Walk
Non-Mendelian Inheritance Patterns

Exploring codominance, incomplete dominance, multiple alleles, and polygenic traits.

Case Study AnalysisGallery WalkInquiry Circle
Sex-Linked Traits and Pedigrees

Analyzing how genes located on sex chromosomes are inherited differently in males and females.

Document MysteryCollaborative Problem-SolvingPeer Teaching
DNA Technology: PCR and Electrophoresis

Understanding the laboratory techniques used to amplify and separate DNA fragments.

Socratic SeminarCase Study AnalysisMock Trial
Genomics and the Human Genome Project

Investigating the impact of sequencing the entire human genome on medicine and society.

Socratic SeminarExpert PanelRole Play
CRISPR and Gene Editing Ethics

Debating the potential and perils of precise genome editing in plants, animals, and humans.

Formal DebatePhilosophical ChairsTown Hall Meeting
Genetic Screening and Counseling

Exploring the methods and ethical considerations of screening for genetic disorders.

Case Study AnalysisSocratic SeminarRole Play
Evolutionary Theory: Darwin's Insights

Examining the observations Darwin made on the HMS Beagle and the logic of his theory of natural selection.

Document MysterySimulation GameSocratic Seminar
Evidence for Evolution: Fossils and Anatomy

Using the physical remains of past life and comparative structures to trace common ancestry.

Gallery WalkStations RotationInquiry Circle
Evidence for Evolution: Embryology & Molecular Biology

Comparing developmental stages and DNA sequences to determine evolutionary distance.

Inquiry CircleConcept MappingJigsaw