The Cell Cycle: Growth and Preparation
Students will investigate the stages of the cell cycle, understanding how cells grow and prepare for division.
About This Topic
Students will investigate the stages of the cell cycle, understanding how cells grow and prepare for division.
Key Questions
- Trace the fate of a glucose molecule through glycolysis, distinguishing the investment phase from the pay-off phase, and explain the chemical logic behind each ATP-consuming and ATP-generating step.
- Analyse why glycolysis produces a net gain of only 2 ATP and 2 NADH per glucose and explain why the regeneration of NAD⁺ is essential for continued glycolytic flux under conditions of limited oxygen supply.
- Evaluate the allosteric regulatory mechanisms that control glycolytic flux at phosphofructokinase-1, predicting how elevated intracellular ATP and citrate concentrations modulate pathway activity in the context of cellular energy status.
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