Nucleotides and Nucleic Acids: DNA and RNA Structure and Information Storage
Students will explore the foundational principles of the cell theory and identify the basic components common to all cells, both prokaryotic and eukaryotic.
Key Questions
- Explain how antiparallel, complementary base pairing in the Watson-Crick double helix model is chemically necessary and functionally essential for accurate DNA replication and information transfer.
- Compare the structural differences between DNA and RNA — deoxyribose versus ribose, thymine versus uracil, and double-stranded versus single-stranded — and relate each structural feature to the respective biological functions of the two molecules.
- Analyse how the Meselson-Stahl experiment using heavy nitrogen isotopes provided conclusive evidence for the semi-conservative model of replication, and explain why the conservative and dispersive models were rejected.
MOE Syllabus Outcomes
Suggested Methodologies
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