Structural Elucidation: NMR, IR, Mass Spectrometry and Multi-Step Synthesis · Semester 2
Green Chemistry: Atom Economy, E-Factor and Sustainable Synthesis
Students will be introduced to the concept of green chemistry and its importance in designing chemical processes that are environmentally friendly and sustainable.
Key Questions
- Calculate the atom economy and E-factor for two competing synthetic routes to the same product, using these metrics to quantitatively compare their environmental credentials and justify a recommendation.
- Evaluate a given industrial chemical process against the 12 Principles of Green Chemistry, identifying the two or three most significant deviations and proposing specific, chemically justified modifications to reduce waste and energy use.
- Analyse the trade-offs between reaction yield, atom economy, solvent choice, and energy input in a multi-step synthesis, constructing a quantitative sustainability scorecard to rank alternative routes.
MOE Syllabus Outcomes
MOE: Environmental Chemistry - MSMOE: Sustainable Practices - MS
Level: JC 2
Subject: Chemistry
Unit: Structural Elucidation: NMR, IR, Mass Spectrometry and Multi-Step Synthesis
Period: Semester 2
Suggested Methodologies
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