Organic Chemistry: Functional Groups and Mechanisms · Chemical Reactions

Carboxylic Acids and Derivatives

Comparing the acidity of carboxylic acids and the reactivity of acyl chlorides and esters.

Key Questions

  1. 1How do electron-withdrawing groups influence the pKa of a carboxylic acid?
  2. 2Why are acyl chlorides significantly more reactive than esters toward hydrolysis?
  3. 3What makes the condensation reaction of an alcohol and acid reversible?

MOE Syllabus Outcomes

MOE: Carboxylic Acids and Derivatives - JC2
Level: JC 2
Subject: Chemistry
Unit: Organic Chemistry: Functional Groups and Mechanisms
Period: Chemical Reactions

Suggested Methodologies

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